Amoxycillin sodium 1000 mg for injection B.P 2009

Company Name
CID
Pharmaceutical Form
vials
Package
Amoxycillin sodium  vials : box contains one vial or 50 vials.
Indications
Amoxycillin is indicated in the treatment of all infections caused by susceptible micro-organism mainly: • Respiratory tract infections: bronchitis, Pharyngitis, uncomplicated community-acquired pneumonia, otitis media and H-influenza infection. • Gastrointestinal tract infections: Enteritis ,bacillary dysentery . Abdominal typhoid and paratyphoid, invasive salmonellosis and in Helicobacter pylori eradication. • Genitourinary tract infections: Cystitis, pyelonephritis, prostatitis, urethritis and gonorrhea. • Skin and soft tissue infection: pyoderma, erysipelas, cellulitis and wound infections. • Listerial meningitis (in combination with other antibiotic). • Endocarditis prophylaxis and treatment. • Anthrax.
Warning & Precautions
Caution is required when using Amoxicid in the following cases: • Known history of allergy (serious and fatal anaphylactic reactions have been reported). • Patients with impaired renal function (dose should be reduced ) . * SGOT and SGPT should be measured during therapy to monitor for liver function abnormalities . * Amoxicid is not known to be harmful during pregnancy or lactation .
Product Type human Dosage For upper respiratory tract, genitourinary tract, skin and soft tissue infections: Adults: 250 mg every 8 hours Children weighing under 20 kg: 20 mg/kg/day in divided doses. These doses may be doubled in severe infections. For lower respiratory tract infections: Adults: 500 mg every 8 hours . These doses may be increased to 1 g in severe infections . Children weighing under 20 kg: 40 mg/kg/day in divided doses. Adverse Reactions • Hypersensitivity reactions like skin rashes and urticaria may occur. • Antibiotic-associated colitis may rarely occur. Contra Indications History of hypersensitivity to penicillins or cephalosporin . Drug Interactions • Allopurinol: increase risk of developing skin rashes. • Bacteriostatic antibiotics (I.e.: tetracycline, Erythromycin): diminish the bactericidal effect of amoxicillin. • Estrogen-containing oral contraceptives: amoxicillin may decrease the contraceptive effect. • Probenecid: blocks the renal tubular excretion of amoxicillin and prolongs its blood level.

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